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Resources and Technical Notes on Differential Display

Technical Support

Technical Notes & Resources
     Optimal arbitrary primer length
     Degeneracy of the arbitrary 13mers
     One-base versus two-base anchored primers
     Number of arbitrary primers and gene coverage
     Comparison of DD with other methodologies
     False Positives in DD
     Frequently asked questions and trouble-shooting
References on Differential Display
Differential Display Methods And Protocols Book
Differential Display Newsletter
Differential Display Summer Workshop

Representative DD Reference Lists compiled by GenHunter


A) Representative DD Reference List (Sorted by Fields of Application)
B) Representative DD Reference List (Sorted Chronologically)



A) Representative DD Reference List

(Sorted by Fields of Application)

Reference numbers underlined in green are from GenHunter customers


Differential Display Methodology

1.Liang, P. and Pardee, A.B.: Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science. 1992, 257:967-71.
4.Liang, P. et al: Distribution and cloning of eukaryotic mRNAs by means of differential display: refinements and optimization. Nucleic Acids Res. 1993, 21:3269-75.
9.Liang, P. et al: Analysis altered gene expression by differential display. Methods in Enzymol. 1995, 254:304-21.
10.Liang, P. et al: Differential display using one-base anchored oligo-dT primers. Nucleic Acids Res. 1994, 22:5763-64.
11.Liang, P. et al: Method of differential display. Methods in Mol. Genetics. (Academic Press) 1994, 5:3-16.
12.Chen, Z. et al: A cautionary note on the reaction tubes for differential display and cDNA amplification in thermal cycling. BioTechniques. 1994, 16:1003-1006.
14.Wang, X. and Feuerstein, G.Z.: Direct sequencing of DNA isolated from mRNA differential display. BioTechniques. 1995, 18:448-52.
15.Trentmann, S.M. et al: Alternatives to 35S as a label for the differential display of eukaryotic messenger RNA. Science. 1995, 267:1186-87.
17.Guimaraes, M.J. et al: Differential Display by PCR: novel findings and applications. Nucleic Acids Res. 1995, 23:1832-33.
26.Liang, P. and Pardee, A.B.: Recent advances in differential display. Current Opinion in Immunology. 1995, 7:274-80.
29.Všgeli-Lange, R. et al: Rapid selection and classification of positive clones generated by mRNA differential display. Nucleic Acids Res. 1996, 24:1385-86.
31.Zhang, H. et al: Differential screening of gene expression difference enriched by differential display. Nucleic Acids Res. 1996, 24:2454-55.
41.Wan, J.S. et al: Cloning differentially expressed mRNAs. Nature Biotechnology. 1996, 14:1685-91.
122.Liang, P.: Factors ensuring successful use of differential display. Methods: A Companion to Methods in Enzymology. 1998, 16:361-364.
130.Matz, M.V. and Lukyanov, S.A: Different strategies of differential display: areas of application. Nucleic Acids Res. 1998, 26:5537-5543.
171.Trenkle, T. et al: Differential display probes for cDNA arrays. BioTechniques. 1999, 27:554-564.
187.Rajeevan, M.S. et al: Chemiluminescent analysis of gene expression on high-density filter arrays. J. Histochemistry & Cytochemistry. 1999, 47:337-342.
193.Brenner, Sydney: Sillycon valley fever. Current Biology. 1999, 9:R671.
207.Bosch, I. et al: Identification of differentially expressed genes from limited amounts of RNA. Nucleic Acids Res. 2000, 28:e27.
254.Liang, P..: Gene discovery using Differential Display. Genetic Engineering News. 2000, 20:37.
255.Mir, K. U.: The hypothesis is there is no hypothesis. Trends in Genetics. 2000, 16:63-64.
256.Wooster, R.: Cancer classification with DNA microarrays, is less more? Trends in Genetics. 2000, 16:327-329.
264.Cho, Y.-J. et al: Multicolor fluorescent differential display. BioTechniques. 2001, 30:562-572.
265.Gibbs, W. W.: Shrinking to enormity: DNA microarrays are reshaping basic biology-but scientists fear they may soon drown in the data. Scientific American. 2001, 284:33-34.
349.Kaserer, K. et al: Construction of cDNA libraries from microdissected benign and malignantthyroid tissue. Laboratory Investigation. 2002, 82:1707-1714.
452.Yang, S. and Liang, P.: Global analysis of gene expression by differential display - A mathematical model. Molecular Biotechnology. 2004, 27:197-208.

Applications in Mammalian Systems

Cancer Research

2.Liang, P. et al: Differential display and cloning of messenger RNAs from human breast cancer versus mammary epithelial cells. Cancer Research. 1992, 52:6966-68.
3.Zhang, L. and Medina, D.: Gene expression screening for specific genes associated with mouse mammary tumor development. Mol. Carcinog. 1993, 8:123-26.
5.Sun, Y. et al: Molecular cloning of five messenger RNAs differentially expressed in preneoplastic or neoplastic JB6 mouse epidermal cells: one is homologous to human tissue inhibitor of metaloproteinase. Cancer Research. 1994, 54:1139-44.
6.Liang, P. et al: Ras activation of genes: Mob-1 as a model. Proc. Natl. Acad. Sci. USA. 1994, 91:12515-125119.
13.Okamato, K. and Beach, D.: Cyclin G is a transcription target of the p53 tumor suppressor protein. The EMBO Journal. 1994, 13: 4816-22.
16.McCarthy, S.A. et al: Rapid induction of heparin-binding epidermal growth factor/diphtheria toxin receptor expression by Raf and Ras oncogenes. Genes & Development. 1995, 9:1953-64.
22.Luna et al: Decreased expression and function of a-2 macroglobulin receptor/low density lipoprotein receptor-related protein in photodynamic therapy-resistant mouse tumor cell. Cancer Research. 1995, 55:1820-23.
23.van Groningen, J.J.M. et al: Identification of melanoma inhibitory activity and other differentially expressed messenger RNAs in human melanoma cell lines with different metastatic capacity by messenger RNA differential display. Cancer Research. 1995, 55:6237-6243.
28.Tan, R. et al: Identification of the Lysyl Oxidase Gene as a target of the Antioncogenic Transcription Factor, IRF-1 and its possible role in tumor suppression. Cancer Research. 1996, 56:2417-21.
32.Scholz, G. et al: Transcriptional down regulation of the nov proto-oncogene in fibroblast transformed by p60v-src Mol. Cell. Biol. 1996, 16:481-86.
33.Francia, G. et al: Identification by differential display of annexin VI, a gene differentially expressed during melanoma progression. Cancer Research. 1996, 56:3855-58.
34.Lehar, S.M. et al: Identification and cloning of EI24, a gene induced by p53 in etoposide-treated cells. Oncogene. 1996, 12:1181-87.
36.Murphy, M. et al: Wild-type p53 negatively regulates the expression of a microtubule-associated protein. Genes & Development. 1996, 10:2971-80.
37.Wang, F.L. et al: Two differentially expressed genes in normal human prostate tissue and in carcinoma. Cancer Research. 1996, 56:3634-37.
54.Topol, L.Z. et al.: Identification of drm, a novel gene whose expression is suppressed in transformed cells and which can inhibit growth of normal but not transformed cells in culture. Mol. Cell. Biol. 1997, 17:4801-10.
55.Israeli, D. et al.: A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis. The EMBO Journal. 1997, 16:4384-92.
58.Fiscella, M. et al.: Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner. Proc. Natl. Acad. Sci. USA. 1997, 94:6048-53.
66.Li, D. et al: Oncogenic Raf-1 induces the expression of non-his-tone chromosomal architectural protein HMGI-C via a p44/p42 mitogen-activated protein kinase-dependent pathway in salivary epithelial cells. J. Biol. Chem. 1997, 272:25062-25070.
74.You, M. et al.: ch-IAP1, a member of the inhibitor-of-apoptosis protein family, is a mediator of the antiapoptotic activity of the v-Rel oncoprotein. Mol. Cell. Biol. 1997, 17:7328-7341.
83.You, L. and Jakowlew, S.B.: Identification of early growth response gene-1 (Egr-1) as a phorbol myristate acetate-induced gene in lung cancer cells by differential mRNA display. American J. of Respiratory Cell & Mol. Biol. 1997, 17:617-624.
84.Riley, H.D. et al: The expression of acylphosphatase is associated with the metastatic phonotype in human colorectal tumors. Carcinogenesis. 1997, 18:2453-2455.
87.Kasukabe, T. et al: TRA1, a novel mRNA highly expressed in leukemogenic mouse monocytic sublines but not in nonleukemogenic sublines. Blood. 1997, 89:2975-2985.
98.Lawlor, E.R. et al: The Ewing tumor family of peripheral primitive neuroectodermal tumors expresses human gastrin-releasing peptide. Cancer Research. 1998, 58:2469-2476.
103.Kotelvets, L. et al: Inhibition by platelet-activating factor of Src- and hepatocyte growth factor-dependent invasiveness of intestinal and kidney epithelial cells: Phosphatidylinosital 3Ő-kinase is a critical mediator of tumor invasion. J. Biol. Chem. 1998, 273:14138-14145.
113.Bein, K. et al: Myb-dependent regulation of thrombospondin 2Ęexpression. Role of mRNA stability. J. Biol. Chem. 1998, 273:21423-21429.
116.Zhang, R. et al: Identification of rCop-1, a new member of the CCN protein family, as a negative regulator for cell transformation. Mol. Cell. Biol. 1998, 18:6131-6141.
117.Castagnino, P. et al: Induction of tissue inhibitor of metallopro-teinases -3 is a delayed early cellular response to hepatocyte growth factor. Oncogene. 1998, 17:481-492.
123.Jo, H. et al: Cloning oncogenic Ras-regulated genes by differential display. Methods: A Companion to Methods in Enzymology. 1998, 16:365-372.
124.Arakawa, H. et al: Identification and characterization of the ARP1 gene, a target for the human acute leukemia ALL1 gene. Proc. Natl. Acad. Sci. USA. 1998, 95:4573-4578.
135.Liu, Y. and Kulesz-Martin, M.F.: Altered gene expression in a clonal epidermal cell model of carcinogenesis identified by RNA differential display. Carcinogenesis. 1998, 19:683-686.
152.Reimer, C.L. et al: Altered regulation of cyclin G in human breast cancer and its specific localization at replication foci in response to DNA damage in p53+/+ cells. J. Biol. Chem. 1999, 274:11022-11029.
155.Taylor, C.T. et al: Critical role of cAMP response element binding protein expression in Hypoxia-elicited induction of epithelial tumor necrosis factor-a. J. Biol. Chem. 1999, 274:19447-19454.
169.Thrash-Bingham, C.A. and Tartof, K.D.: aHIF: A natural antisense transcript overexpressed in human renal cancer and during hypoxia. J. Natl. Cancer Inst. 1999, 91:a143-a151.
174.Hisamatsu, T. et al: Interferon-inducible gene family 1-8U expression in colitis-associated colon cancer and severely inflamed mucosa in ulcerative colitis. Cancer Research. 1999, 59:5927-5931.
175.Fournier, M.V. et al: Identification of a gene encoding a human oxysterol-binding protein-homologue: a potential general molecular marker for blood dissemination of solid tumors. Cancer Research. 1999, 59:3748-3753.
176.Bussemakers, M.J.G. et al: DD3: A new prostate-specific gene, highly overexpressed in Prostate Cancer. Cancer Research. 1999, 59:5975-5979.
178.Park, B.-W. et al: Induction of the Tat-binding protein 1 gene accompanies the disabling of oncogenic erbB receptor tyrosine kinases. Proc. Natl. Acad. Sci. USA. 1999, 96:6434-6438.
180.Cmarik, J.L. et al: Differentially expressed protein Pdcd4 inhibits tumor promoter-induced neoplastic transformation. Proc. Natl. Acad. Sci. USA 1999, 96:14037-14042.
181.Lo, P.-K. et al: Identification of a novel mouse p53 target gene DDA3. Oncogene. 1999, 18:7765-7774.
201.Tanaka, H. et al: A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage. Nature. 2000, 404:42-49.
208.Chen, H.-M. et al: AZU-1: A candidate breast tumor suppressor and biomarker for tumor progression. Mol. Biol. of the Cell. 2000, 11:1357-1367.
226.Tanaka, T. et al: Expression of stress-response and cell proliferation genes in renal cell carcinoma induced by oxidative stress. American Journal of Pathology. 2000, 156:2149-2157.
228.Zhang, Z. and DuBois, R.N.: Par-4, a proapoptotic gene, is regulated by NSAIDs in human colon carcinoma cells. Gastroenterology. 2000, 118:1012-1017.
233.Foca, C. et al: Identification and partial characterization of differentially expressed mRNAs in normal human endometria and endometrial carcinomas by differential display RT-PCR. Molecular Human Reproduction. 2000, 6:712-718.
239.Lin, Y. et al: Pidd, a new death-domain-containing protein, is induced by p53 and promotes apoptosis. Nature Genetics. 2000, 26:124-127.
243.Ohki, R. et al: Reprimo, a new candidate mediator of the p53-mediated cell cycle arrest at the G(2) phase J. Biol. Chem. 2000, 275:22627-22630.
249.Li, P.-X. et al: Placental transforming growth factor-b is a downstream mediator of the growth arrest and apoptotic response of tumor cells to DNA damage and p53 overexpression. J. Biol. Chem. 2000, 275:20127-20135.
250.Zhang, R. et al: Identification of a novel ligand-receptor pair constitutively activated by Ras oncogenes. J. Biol. Chem. 2000, 275:24436-24443.
252.Wu, H. et al: Autocrine gastrins in colon cancer cells up-regulate cytochrome c oxidase Vb and down-regulate efflux of cytochrome c and activation of caspase-3. J. Biol. Chem. 2000, 275:32491-32498.
253.Gu, Z. et al: ei24, a p53 response gene involved in growth suppression and apoptosis. Mol. Cell. Biol. 2000, 20:233-241.
257.Oda, E.,et al: Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science. 2000, 288:1053-1058.
258.Wang, D. et al: MGSA/GRO-mediated melanocyte transformation involves induction of Ras expression. Oncogene. 2000, 19:4647-4659.
259.Frederick, M.J. et al: In vivo expression of the novel CXC chemokine BRAK in normal and cancerous human tissue. American Journal of Pathology. 2000, 156:1937-1950.
261.Deininger, M.W.N. et al: BCR-ABL tyrosine kinase activity regulates the expression of multiple genes implicated in the pathogenesis of chronic myeloid leukemia. Cancer Research. 2000, 60:2049-2055.
263.Bueno, R. et al: The a folate receptor is highly activated in malignant pleural mesothelioma. J. Thoracic & Cardiovascular Surgery. 2001, 121:225-233.
282.Lo, P. et al: Identification of a mouse thiamine transporter gene as a direct transcriptional target for p53. J. Biol. Chem. 2001, 276:37186-37193.
287.Karumanchi, S.A. et al: VHL tumor suppressor regulates Cl-/HCO3- exchange and Na+/H+ exchange activities in renal carcinoma cells. Physiological Genomics. 2001, 5:119-128.
292.Smith, B.A. et al: Identification of genes involved in human urothelial cell-matrix interactions: implications for the progression pathways of malignant urothelium. Cancer Research. 2001, 61:1678-1685.
293.Hsu, N. et al: Overexpression of dihydrodiol dehydrogenase as a prognostic marker of non-small cell lung cancer. Cancer Research. 2001, 61:2727-2731.
294.Mariani, L. et al: Identification and validation of P311 as a glioblastoma invasion gene using laser capture microdissection. Cancer Research. 2001, 61:4190-4196.
295.Shridhar, V. et al: Loss of expression of a new member of the DNAJ protein family confers resistance to chemotherapeutic agents used in the treatment of ovarian cancer. Cancer Research. 2001, 61:4258-4265.
296.Dong, G. et al: Molecular profiling of transformed and metastatic murine squamous carcinoma cells by differential display and cDNA microarray reveals altered expression of multiple genes related to growth, apoptosis, angiogenesis, and the NF-B signal pathway. Cancer Research. 2001, 61:4797-4808.
297.Matsuyama, A. et al: Hepatoma-derived growth factor is associated with reduced sensitivity to irradiation in esophageal cancer. Cancer Research. 2001, 61:5714-5717.
298.Segawa, N. et al: Phosphorylation of mitogen-activated protein kinase is inhibited by calcitonin in DU145 prostate cancer cells. Cancer Research. 2001, 61:6060-6063.
299.Luker, K.E. et al: Overexpression of IRF9 confers resistance to antimicrotubule agents in breast cancer cells. Cancer Research. 2001, 61:6540-6547.
300.Chung, J. et al: Novel transmembrane GTPase of non-small cell lung cancer identified by mRNA differential display. Cancer Research. 2001, 61:8873-8879.
317.Yiu, G.K. et al: SPARC (Secreted Protein Acidic and Rich in Cysteine) induces apoptosis in ovarian cancer cells. American Journal of Pathology. 2001, 159:609-622.
333.Mariani, L. et al: Death-associated Protein 3 (Dap-3) is overexpressed in invasive glioblastoma cells in vivo and in glioma cell lines with induced motility phenotype in vitro. Clinical Cancer Research. 2001, 7:2480-2489.
349.Kaserer, K. et al: Construction of cDNA libraries from microdissected benign and malignantthyroid tissue. Laboratory Investigation. 2002, 82:1707-1714.
350.Wang, M. et al: Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2. J. Biol. Chem. 2002, 277:7341-7347.
351.Deng, H.B. et al: Increased expression of dihydrodiol dehydrogenase induces resistance to cisplatin in human ovarian carcinoma cells. J. Biol. Chem. 2002, 277:15035-15043.
355.Kim, D. et al: GADD153-mediated anticancer effects of N-(4-hydroxyphenyl)retinamide on human hepatoma cells. J. Biol. Chem. 2002, 277:38930-38938.
358.Brandt, B. et al: Early placenta insulin-like growth factor (pro-EPIL) is overexpressed and secreted by c-erbB-2-positive cells with high invasion potential. Cancer Research. 2002, 62:1020-1024.
359.Shekhar, M.P.V. et al: Rad6 overexpression induces multinucleation, centrosome amplification, abnormal mitosis, aneuploidy, and transformation. Cancer Research. 2002, 62:2115-2124.
360.Neef, R. et al: Identification of the human PHLDA1/TDAG51 gene: down-regulation in metastatic melanoma contributes to apoptosis resistance and growth deregulation. Cancer Research. 2002; 62:5920-5929.
367.Schultheis, B. et al: Overexpression of SOCS-2 in advanced stages of chronic myeloid leukemia: possible inadequacy of a negative feedback mechanism. Blood. 2002, 99:1766-1775.
370.Cheng, Q. et al: Identification of molecular markers for the early detection of human squamous cell carcinoma of the uterine cervix. British Journal of Cancer. 2002, 86:274-281.
377.Gordon, G.J. et al: Inhibitor of apoptosis protein-1 promotes tumor cell survival in mesothelioma. Carcinogenesis. 2002, 23:1017-1024.
379.Utsunomiya, T. et al: G protein g7 expression as a new clinicopathological marker in patients with intrahepatic cholangiocarcinoma. Archives of Surgery. 2002, 137:181-185.
382.Liu, S. et al: Down-regulation of Annexin A10 in hepatocellular carcinoma is associated with vascular invasion, early recurrence, and poor prognosis in synergy with p53 mutation. American Journal of Pathology. 2002, 160:1831-1837.
383.Steenbergen, R.D.M. et al: Down-regulation of GATA-3 expression during human papillomavirus-mediated immortalization and cervical carcinogenesis. American Journal of Pathology. 2002, 160:1945-1951.
386.Ahola, T.M. et al: Progestin upregulates G-protein-coupled receptor 30 in breast cancer cells. European J. Biochem. 2002, 269:2485-2490.
387.Gabrilovich, D.I. et al: H1ˇ histone and differentiation of dendritic cells. A molecular target for tumor-derived factors. J. Leukoc. Biol. 2002, 72:285-296.
389.Wightman, J. et al: Retinoic acid-induced growth arrest and differentiation: retinoic acid up-regulates CD32 (FcgRII) expression, the ectopic expression of which retards the cell cycle. Mol. Cancer Therapeutics. 2002, 1:493-506.
413.Mahloogi, H. et al: Overexpression of the calcium sensor visinin-like protein-1 leads to a cAMP-mediated decrease of in vivo and in vitro growth and invasiveness of squamous cell carcinoma Cells. Cancer Research. 2003, 63:4997-5004.
415.Gonzalez, H.E. et al: Identification of 9 genes differentially expressed in head and neck squamous cell carcinoma. Archives of Otolaryngology-Head and Neck Surgery. 2003, 129:754-759.
424.Inagaki, T. et al: The retinoic acid-responsive proline-rich protein is identified in promyeloleukemic HL-60 cells. J. Biol. Chem. 2003, 278:51685-51692.
429.Lemaire, F. et al: Differential expression profiling of head and neck squamous cell carcinoma (HNSCC). British Journal of Cancer. 2003, 89:1940-1949.
431.Ko, J. et al: Identification and differential expression of novel human cervical cancer oncogene HCCR-2 in human cancers and its involvement in p53 stabilization. Oncogene. 2003, 22:4679-4689.
432.Leng, R.P. et al: Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation. Cell. 2003, 112:779-791.
439.Lee, Y.I. et al: Human hepatitis B virus-X protein alters mitochondrial function and physiology in human liver cells. J. Biol. Chem. 2004, 279:15460-15471.
441.Stein, S. et al: NDRG1 is necessary for p53-dependent apoptosis. J. Biol. Chem. 2004, 279:48930 - 48940.
443.Tanaka, T. et al: Redox regulation of annexin 2 and its implications for oxidative stress-induced renal carcinogenesis and metastasis. Oncogene. 2004, 23:3980-3989.
444.Dong, G. et al: Metastatic squamous cell carcinoma cells that overexpress c-Met exhibit enhanced angiogenesis factor expression, scattering and metastasis in response to hepatocyte growth factor. Oncogene. 2004, 23:6199-6208.
445.Karp, C.M. et al: Identification of HRPAP20: A novel phosphoprotein that enhances growth and survival in hormone-responsive tumor cells. Cancer Research. 2004, 64:1016-1025.
446.Arnold, N.B. et al: Thioredoxin is downstream of Smad7 in a pathway that promotes growth and suppresses cisplatin-induced apoptosis in pancreatic cancer. Cancer Research. 2004, 64:3599-3606.
447.Fang, M.Z. et al: Over-expression of gastrin-releasing peptide in human esophageal squamous cell carcinomas. Carcinogenesis. 2004, 25:865-871.
448.Ha, S.-A. et al: Cancer-associated expression of minichromosome maintenance 3 gene in several human cancers and its involvement in tumorigenesis. Clinical Cancer Research. 2004, 10:8386-8395.
449.Mori, M. et al: Expression of apoptosis inhibitor protein Mcl1 linked to neuroprotection in CNS neurons. Cell Death and Differentiation. 2004, 11:1223-1233.
450.Li, S. et al: Preferential expression of hPGFS in primary SCCHN and tumour cell lines derived from respiratory and digestive organs. British Journal of Cancer. 2004, 90:1093-1099.
451.Bharti, S. et al: Novel membrane protein shrew-1 targets to cadherin-mediated junctions in polarized epithelial cells. Mol. Biol. of the Cell. 2004, 15:397-406.
471.Thomas, E.K. et al: Endo180 binds to the c-terminal region of type I collagen. J. Biol. Chem., 2005, 280:22596-22605.
473.Park, J.-H. et al: Identification of the genes involved in enhanced fenretinide-induced apoptosis by parthenolide in human hepatoma cells. Cancer Research. 2005, 65:2804-2814.
474.Jacques, C. et al: Two-step differential expression analysis reveals a new set of genes involved in thyroid oncocytic tumors. J. Clin. Endocrinology & Metabolism. 2005, 90:2314-2320.
475.Bardeesy, N. et al: Role of epidermal growth factor receptor signaling in RAS-driven melanoma. Mol. Cell. Biol. 2005, 25:4176-4188.
476.Yoo, Y.A. et al: Mitochondrial ribosomal protein L41 suppresses cell growth in association with p53 and p27Kip1. Mol. Cell. Biol. 2005, 25:6603-6616.
477.Zhang, H.M. et al: Gamma interferon-inducible protein 10 induces HeLa cell apoptosis through a p53-dependent pathway initiated by suppression of human papillomavirus type 18 E6 and E7 expression. Mol. Cell. Biol. 2005, 25:6247-6258.
479.Zhang, Y. et al: The human mineral dust-induced gene, mdig, is a cell growth regulating gene associated with lung cancer. Oncogene. 2005, 24:4873-4882.
480.Carles, A. et al: Head and neck squamous cell carcinoma transcriptome analysis by comprehensive validated differential display. Oncogene. 2005, 10.1038/sj.onc.1209203.
494.Miki, Y. et al: Expression of the steroid and xenobiotic receptor and its possible target gene, organic anion transporting polypeptide-A, in human breast carcinoma. Cancer Research. 2006, 66:535-542.
495.Culjkovic, B. et al: eIF4E is a central node of an RNA regulon that governs cellular proliferation. J. Cell Biology. 2006, 175:415-426.
496.Ishimaru, N. et al: Novel role for RbAp48 in tissue-specific, estrogen deficiency-dependent apoptosis in the exocrine glands. Mol. Cell. Biol. 2006, 26:2924-2935.
497.Isachenko, N. et al: High expression of shMDG1 gene is associated with low metastatic potential of tumor cells. Oncogene. 2006, 25:317-322.
498.Mai, R.-T. et al: Hepatitis C virus core protein recruits nucleolar phophoprotein B23 and coactivator p300 to relieve the repression effect of transcriptional factor YY1 and B23 gene expression. Oncogene. 2006, 25:448-462.
499.Chen, J. et al: The carbonic anhydrase I locus contains a c-Myb target promoter and modulates differentiation of murine erythroleukemia cells. Oncogene. 2006, 25:2758 - 2772.
500.Chen, Y.-J. et al: DSG3 is overexpressed in head neck cancer and is a potential molecular target for inhibition of oncogenesis. Oncogene. 2006, DOI 10.1038/sj.onc.1209802.
501.Tong, S. et al: The activation of TC10, a Rho small GTPase, contributes to v-Rel-mediated transformation. Oncogene. 2006, DOI 10.1038/sj.onc.1210023.

Apoptosis and Cell Death

74.You, M. et al.: ch-IAP1, a member of the inhibitor-of-apoptosis protein family, is a mediator of the antiapoptotic activity of the v-Rel oncoprotein. Mol. Cell. Biol. 1997, 17:7328-7341.
91.Padanilam, B.J. and Hammerman, M.R.: Ischemia-induced receptor for activated C kinase (RACK1) expression in rat kidneys. Am. J. Physiol: Renal Physiology. 1997, 272:F160-166.
92.Lewington, A.J. et al: Induction of calcyclin after ischemic injury to rat kidney. Am. J. Physiol: Renal Physiology. 1997, 273:F380-385.
97.Wu, M.X. et al: IEX-1L, an apoptosis inhibitor involved in NF-kB-mediated cell survival. Science. 1998, 281:998-1001.
161.Duan, H. et al: SAG, a novel zinc RING finger protein that protects cells from apoptosis induced by redox agents. Mol. Cell. Biol. 1999, 19:3145-3155.
170.Schneider, T.J. et al: A novel gene coding for a Fas apoptosis inhibitory molecule (FAIM) isolated from inducibly Fas-resistant B lymphocytes. J. Experimental Medicine. 1999, 189:949-956.
179.Garcia-Domingo, D. et al: DIO-1 is a gene involved in onset of apoptosis in vitro, whose misexpression disrupts development. Proc. Natl. Acad. Sci. USA. 1999, 96:7992-7997.
186.Holthofer, H. et al: Altered gene expression and functions of mitochondria in human nephrotic syndrome. The FASEB Journal. 1999, 13:523-532.
192.Gomes, I. et al: A proline- and glutamine-rich protein promotes apoptosis in neuronal cells. J. Neurochemistry. 1999, 73:612-622.
239.Lin, Y. et al: Pidd, a new death-domain-containing protein, is induced by p53 and promotes apoptosis. Nature Genetics. 2000, 26:124-127.
249.Li, P.-X. et al: Placental transforming growth factor-b is a downstream mediator of the growth arrest and apoptotic response of tumor cells to DNA damage and p53 overexpression. J. Biol. Chem. 2000, 275:20127-20135.
252.Wu, H. et al: Autocrine gastrins in colon cancer cells up-regulate cytochrome c oxidase Vb and down-regulate efflux of cytochrome c and activation of caspase-3. J. Biol. Chem. 2000, 275:32491-32498.
257.Oda, E.,et al: Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science 2000, 288:1053-1058.
278.Moriwaki, Y. et al: Mycobacterium bovis Bacillus calmette-guerin and its cell wall complex induce a novel lysosomal membrane protein, SIMPLE, that bridges the missing link between lipopolysaccharide and p53-inducible Gene, LITAF(PIG7), and estrogen-inducible gene, EET-1. J. Biol. Chem. 2001, 276:23065-23076.
441.Stein, S. et al: NDRG1 is necessary for p53-dependent apoptosis. J. Biol. Chem. 2004, 279:48930 - 48940.
446.Arnold, N.B. et al: Thioredoxin is downstream of Smad7 in a pathway that promotes growth and suppresses cisplatin-induced apoptosis in pancreatic cancer. Cancer Research. 2004, 64:3599-3606.
449.Mori, M. et al: Expression of apoptosis inhibitor protein Mcl1 linked to neuroprotection in CNS neurons. Cell Death and Differentiation. 2004, 11:1223-1233.
460.Jaleel, M.A. et al: Stromal cell-derived factor-1 (SDF-1) signalling regulates human placental trophoblast cell survival. Molecular Human Reproduction. 2004, 10:901-909.
473.Park, J.-H. et al: Identification of the genes involved in enhanced fenretinide-induced apoptosis by parthenolide in human hepatoma cells. Cancer Research. 2005, 65:2804-2814.
477.Zhang, H.M. et al: Gamma interferon-inducible protein 10 induces HeLa cell apoptosis through a p53-dependent pathway initiated by suppression of human papillomavirus type 18 E6 and E7 expression. Mol. Cell. Biol. 2005, 25:6247-6258.
492.Tang, D.C. et al: The hydroxyurea-induced small GTP-binding protein SAR modulates gamma-globin gene expression in human erythroid cells. Blood. 2005, 106:3256-3263.
496.Ishimaru, N. et al: Novel role for RbAp48 in tissue-specific, estrogen deficiency-dependent apoptosis in the exocrine glands. Mol. Cell. Biol. 2006, 26:2924-2935.
503.Schnell, S. et al: Gimap4 accelerates T-cell death. Blood. 2006, 108:591-599.

Toxicology and Toxin Inducible Genes

96.Levy, F.H. and Kelly, D.P.: Regulation of ATP synthase subunit e gene expression by hypoxia: cell differentiation stage-specific control. Am. J. Physiol: Cell Physiology. 1997, 272:C457-465.
104.Gao, L. et al: A novel response to dioxin. Induction of ecto-ATPase gene expression. J. Biol. Chem. 1998, 273:15358-15365.
121.Zhou, D. et al: Cap43, a novel gene specifically induced by Ni2+ compounds. Cancer Research. 1998, 58:2182-2189.
183.Miura, N. et al: Protective effects of triterpene compounds against the cytotoxicity of cadmium in HepG2 cells. Mol. Pharmacology. 1999, 56:1324-1328.
315.Thai, S. et al: Detection of early gene expression changes by differential display in the livers of mice exposed to dichloroacetic acid. Carcinogenesis. 2001, 22:1317-1322.

Heart Disease

7.Utans, U. et al: Chronic cardiac rejection: identification of five up-regulated genes in transplanted hearts by differential mRNA display. Proc. Natl. Acad. Sci. USA. 1994, 91:6463-67.
8.Russell, M. et al: Identification and up-regulation of galactose/N-acetylgalactosamine macrophage lectin in rat cardiac allografts with arteriosclerosis. J. Clin. Invest. 1994, 94:722-30.
24.Autieri et al: Use of differential display to identify differentially expressed mRNAs induced by rat carotid balloon angioplasty. Laboratory Investigation. 1995, 72:656-61.
35.Chen, J. et al: Identification of differentially expressed genes in rat aortic allograft vasculopathy. American Journal of Pathology. 1996, 149:597-611.
45.Kokame, K. et al: Homocysteine-respondent genes in vascular endothelial cells identified by differential display analysis. GRP78/BiP and novel genes. J. Biol. Chem. 1996, 271:29659-29665.
68.Jeyaseelan, R. et al: A novel cardiac-restricted target for doxorubicin. Carp, a nuclear modulator of gene expression in cardiac progenitor cells and cardiomyocytes. J. Biol. Chem. 1997, 272:22800-22808.
69.Jeyaseelan, R. et al: Molecular mechanisms of doxorubicin-induced cardiomyopathy. Selective suppression of reiske iron-sulfur protein, ADP/ATP translocase, and phosphofructokinase genes is associated with ATP depletion in rat cardiomyocytes. J. Biol. Chem. 1997, 272:5828-5832.
86.Lee, M.-E. and Haber, E.: Collagen VIII is expressed by vascular smooth muscle cells in response to vascular injury. Circulation Research. 1997, 80:532-541.
94.Sirokman, G. et al: Endogenous retroviral transcripts in myocytes from spontaneously hypertensive rats. Hypertension. 1997, 30:88-93.
142.Wigle, D.A. et al: AML1-like transcription factor induces serine elastase activity in ovine pulmonary artery smooth muscle cells. Circulation Research. 1998, 252-263.
162.Tang, S.Q. et al: Enhancement of endothelial cell migration and in vitro tube formation by TAP20, a novel beta 5 integrin-modulating, PKC theta-dependent protein. J. Cell Biology. 1999, 147:1073-1083.
164.Zibara, K. et al: Identification and cloning of a new gene (2A3-2), homologous to human translational elongation factor, upregulated in a proliferating rat smooth muscle cell line and in carotid hyperplasia. Arterioscler, Thromb. & Vasc. Biol. 1999, 19:1650-1657.
165.Yang, D. et al: Viral myocarditis: identification of five differentially expressed genes in coxsackievirus B3-infected mouse heart. Circulation Research. 1999, 84:704-712.
166.Rittner, H.L. et al: Tissue-destructive macrophages in giant cell arteritis. Circulation Research. 1999, 84:1050-1058.
197.Singh, K. et al: Myocardial osteopontin expression coincides with the development of heart failure. Hypertension. 1999, 33:663-670.
260.Sheikh-Hamad, D. et al: Regulation of stanniocalcin in MDCK cells by hypertonicity and extracellular calcium. Am. J. Physiol: Renal Physiology. 2000, 278:F417-424.
276.Nechiporuk, T et al: ETL, a novel seven-transmembrane receptor that is developmentally regulated in the heart. ETL is a member of the secretin family and belongs to the epidermal growth factor-seven-transmembrane subfamily. J. Biol. Chem. 2001, 276: 4150-4157.
281.Hosoda, T. et al: A novel myocyte-specific gene Midori promotes the differentiation of P19CL6 cells into cardiomyocytes. J. Biol. Chem. 2001, 276:35978-35989.
289.Ngimbous, B.B. et al: Heart transplantation changes the expression of distinct gene families. Physiological Genomics. 2001, 7:115-126.
348.Wolf, G. et al: Angiotensin IIŐs antiproliferative effects mediated through AT2-receptors depend on down-regulation of SM-20. Laboratory Investigation. 2002, 82:1305-1317.
376.Nickenig, G. et al: Redox-sensitive vascular smooth muscle cell proliferation is mediated by GKLF and Id3 in vitro and in vivo. FASEB J. 2002, 16:1077-1086.
384.Mueller, C. et al: Identification of a novel redox-sensitive gene, Id3, which mediates angiotensin IIĐinduced cell growth. Circulation. 2002, 105:2423-2428.
416.Unoki, H. et al: Up-regulation of cyr61 in vascular smooth muscle cells of spontaneously hypertensive rats. Laboratory Investigation. 2003, 83:973-982.
420.Thorne, G.D. and Paul, R.J.: Effects of organ culture on arterial gene expression and hypoxic relaxation: role of the ryanodine receptor. Am. J. Physiol: Cell Physiology. 2003, 284:C999-1005.
425.Villablanca, A.C. et al: Differential regulation of gene expression by ovariectomy in mouse aorta. Physiological Genomics. 2003, 12:175-185.
427.Thorne, G.D. and Paul, R.J.: Effects of organ culture on arterial gene expression and hypoxic relaxation: role of the ryanodine receptor. Am. J. Physiol: Lung Cell. & Molec. Physiol. 2003, 284:C999-1005.
504.Ishihata, A. and Katano, Y.: Investigation of differentially expressed genes in the ventricular myocardium of senescent rats. Ann. N.Y. Acad. Sci. 2006, 1067:142-151.

Developmental Biology and Cell Differentiation

18.Guimaraes, M.J.: et al: A new approach to the study of haematopoietic development in the yolk sac and embryoid bodies. Development. 1995, 121: 3335-46.
39.Dietz, U.H. and Sandell, L.J.: Cloning of a retinoic acid-sensitive mRNA expressed in cartilage and during chondrogenesis. J. Biol. Chem. 1996, 271:3311-16.
47.Bush, E.W. et al: Overexpression of myotonic dystrophy kinase in BC[(3)]H1 cells induces the skeletal muscle phenotype. J. Biol. Chem. 1996, 271:548-552.
72.Catalano R.D. et al: Differential display to identify and isolate novel genes expressed during spermatogenesis. Molecular Human Reproduction. 1997, 3:215-221.
77.Rafaeloff, R. et al: Cloning and sequencing of the pancreatic islet neogenesis associated protein (INGAP) and its expression in islet neogenesis in hamsters. J. Clin. Invest. 1997, 99:2100-2109.
81.Lorentz, O. et al: Key role of the Cdx2 homeobox gene in extracellular matrix-mediated intestinal cell differentiation. J. Cell Biology. 1997, 139:1553-1565.
82.Schwiebert, L.M. et al: Identification of novel inducible genes in airway epithelium. American J. of Respiratory Cell & Mol. Biol. 1997, 17:106-113.
85.Maekawa, T.L. et al: A novel gene (drad-1) expressed in hematopoiesis-supporting stromal cell lines, ST2, PA6 and A54 preadipocytes: Use of mRNA differential display. Stem Cells. 1997, 15:334-339.
88.Karginova, E.A. et al: Zis: A developmentally regulated gene expressed in juxtaglomerular cells. Am. J. Physiol: Cell Physiology. 1997, 273:731F-738F.
93.Karginova, E.A. et al: Zis: a developmentally regulated gene expressed in juxtaglomerular cells. Am. J. Physiol: Renal Physiology. 1997, 273:F731-738.
101.Noel, L.S. et al: RoBo-1, a novel member of the urokinase plasminogen activator receptor/CD59/Ly-6/snake toxin family selectively expressed in rat bone and growth plate cartilage. J. Biol. Chem. 1998, 273:3878-3883.
105.Takeda, K. et al: Identification of a novel bone morphogenetic protein-responsive gene that may function as a noncoding RNA. J. Biol. Chem. 1998, 273:17079-17085.
112.Hu, S-I et al: Human HtrA, an evolutionarily conserved serine protease identified as a differentially expressed gene product in osteoarthritic cartilage. J. Biol. Chem. 1998, 273:34406-34412.
128.Tohonen, V. et al: Testatin: A cystatin-related gene expressed during early testis development. Proc. Natl. Acad. Sci. USA. 1998, 95:14208-14213.
129.Semizarov, D. et al: A lineage-specific protein kinase crucial for myeloid maturation. Proc. Natl. Acad. Sci. USA. 1998, 95:15412-15417.
140.Dovat, S. et al: Targeted identification of zinc finger genes expressed in rat lungs. Am. J. Physiol: Lung Cell. & Molec. Physiol. 1998, 275:30L-37L.
151.Hiki, K. et al: Cloning, characterization, and chromosomal location of a novel human K+-Cl- cotransporter. J. Biol. Chem. 1999, 274:10661-10667.
153.Murdock, D.G et al: Up-regulation of nuclear and mitochondrial genes in the skeletal muscle of mice lacking the heart/muscle isoform of the adenine nucleotide translocator. J. Biol. Chem. 1999, 274:14429-14433.
154.Kaiser, A. et al: All-trans-retinoic acid-mediated growth inhibition involves inhibition of human kinesin-related protein HsEg5. J. Biol. Chem. 1999, 274:18925-18931.
156.Hollnagel, A. et al: Id genes are direct targets of bone morphogenetic protein induction in embryonic stem cells. J. Biol. Chem. 1999, 274:19838-19845.
157.Chen, D. et al: Cloning and uterus/oviduct-specific expression of a novel estrogen-regulated gene (ERG1). J. Biol. Chem. 1999, 274:32215-32224.
158.Akiyama, H. et al: Molecular cloning and biological activity of a novel Ha-Ras suppressor gene predominantly expressed in skeletal muscle, heart, brain, and bone marrow by differential display using clonal mouse EC cells, ATDC5. J. Biol. Chem. 1999, 274:32192-32197.
163.Xu. B. et al: Identification of a stress-induced protein during human trophoblast differentiation by differential display analysis. Biol. Reproduction. 1999, 61:681-686.
167.Weiler, S.R. et al: D3: A gene induced during myeloid cell differentiation of Linlo c-Kit+ Sca-1+ progenitor cells. Blood. 1999, 93:527-536.
168.Walden, P.D. et al: Mitogenic activation of human prostate-derived fibromuscular stromal cells by bradykinin. British J. Pharmacology. 1999, 127:220-226.
185.Lurton, J. et al: Isolation of a gene product expressed by a subpopulation of human lung fibroblasts by Differential Display. American J. Respiratory Cell & Mol. Biol. 1999, 20:327-331.
203.Antonio, C. et al: Xkid, a chromokinesin required for chromosome alignment on the metaphase plate. Cell. 2000, 102:425-435.
220.Schmidt, J.V. et al: The Dlk1 and Gtl2 genes are linked and reciprocally imprinted. Genes & Development. 2000, 14:1997-2002.
227.Hashimoto, M. et al: Isolation and localization of type IIb Na/Pi cotransporter in the developing rat lung. American Journal of Pathology. 2000, 157:21-27.
229.Zhang, M. et al: Light ethanol consumption enhances liver regeneration after partial hepatectomy in rats. Gastroenterology. 2000, 118:1333-1339.
230.Fujii, S. et al: Differential expression of neuroendocrine-specific protein in form-deprived chick eyes. Invest. Ophthalmology & Vis. Sci. 2000, 41:1533-1541.
231.Feldkaemper, M.P. et al: Changes in retinal and choroidal gene expression during development of refractive errors in chicks. Invest. Ophthalmology & Vis. Sci. 2000, 41:1623-1628.
234.Fritsche, J. et al: Molecular cloning and characterization of a human metalloprotease disintegrin - a novel marker for dendritic cell differentiation. Blood. 2000, 96:732-739.
251.Haertel-Wiesmann, M. et al: Regulation of cyclooxygenease-2 and periostin by Wnt-3 in mouse mammary epithelial cells. J. Biol. Chem. 2000, 275:32046-32051.
277.Jheon, A.H. et al: Characterization of a novel KRAB/C2H2 zinc finger transcription factor involved in bone development. J. Biol. Chem. 2001, 276:18282-18289.
281.Hosoda, T. et al: A novel myocyte-specific gene Midori promotes the differentiation of P19CL6 cells into cardiomyocytes. J. Biol. Chem. 2001, 276:35978-35989.
284.Kearns, A.E. et al: Cloning and characterization of a novel protein kinase that impairs osteoblast differentiation in vitro. J. Biol. Chem. 2001, 276:42213-42218.
285.Gori, F. et al: Cloning and characterization of a novel WD-40 repeat protein that dramatically accelerates osteoblastic differentiation. J. Biol. Chem. 2001, 276:46515-46522.
288.Li, H. et al: Rat mitochondrial ATP synthase ATP5G3: cloning and upregulation in pancreas after chronic ethanol feeding. Physiological Genomics. 2001, 6:91-98.
290.Jhaveri, M.S. et al: Impact of extracellular folate levels on global gene expression. Mol. Pharmacology. 2001, 60:1288-1295.
307.Silverman, M.D. et al: Cell adhesion molecule expression in cultured human iris endothelial cells. Invest. Ophthalmology & Vis. Sci. 2001, 42:2861-2866.
308.Weterings, K. et al: Regional localization of suspensor mRNAs during early embryo development. Plant Cell. 2001, 13:2409-2425.
312.Gregorio-King, C.C. et al: ORP-3, a human oxysterol-binding protein gene differentially expressed in hematopoietic cells. Blood. 2001, 98:2279-2281.
316.Bell, S.E. et al: Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling. J. Cell Science. 2001, 114:2755-2773.
318.Doi, M. et al: Light-induced phase-delay of the chicken pineal circadian clock is associated with the induction of cE4bp4, a potential transcriptional repressor of cPer2 gene. Proc. Natl. Acad. Sci. USA. 2001, 98:8089-8094.
325.Minami, N. et al: Analysis of gene expression in mouse 2-cell embryos using fluorescein differential display: comparison of culture environments. Biol. Reproduction. 2001, 64:30-35.
327.Iida, H. et al: Spermatid-specific expression of Iba1, an ionized calcium binding adapter molecule-1, in rat testis. Biol. Reproduction. 2001, 64:1138-1146.
328.Ma, J. et al: Regulation of zygotic gene activation in the preimplantation mouse embryo: global activation and repression of gene expression. Biol. Reproduction. 2001, 64:1713-1721.
329.Robert, C. et al: Differential display and suppressive subtractive hybridization used to identify granulosa cell messenger RNA associated with bovine oocyte developmental competence. Biol. Reproduction. 2001, 64:1812-1820.
344.Torres, M.S.T. et al: Assessment and application of laser microdissection for analysis of gene expression in the rhesus monkey endometrium. Biol. Reproduction. 2002, 67:1067-1072.
345.Baran, N. et al: Characterization of a prolactin-regulated gene in reproductive tissues using the prolactin receptor knockout mouse model. Biol. Reproduction. 2002, 66:1210-1218.
346.Doiguchi, M. et al: Complementary DNA cloning and characterization of rat spergen-1, a spermatogenic cell-specific gene-1, containing a mitochondria-targeting signal. Biol. Reproduction. 2002, 66:1462-1470.
347.Espey, L.L. and Richards, J.S.: Temporal and spatial patterns of ovarian gene transcription following an ovulatory dose of gonadotropin in the rat. Biol. Reproduction. 2002, 67:1662-1670.
352.Christian, M. et al: Cyclic AMP-induced forkhead transcription factor, FKHR, cooperates with CCAAT/enhancer-binding protein b in differentiating human endometrial stromal cells. J. Biol. Chem. 2002, 277:20825-20832.
353.Chipuk, J.E. et al: Identification and characterization of a novel rat ov-serpin family member, trespin. J. Biol. Chem. 2002, 277:26412-26421.
361.Haddad, A. et al: New class of cargo protein in tetrahymena thermophila dense core secretory granules. Eukaryotic Cell. 2002, 1:583-593.
368.Giraudier, S. et al: Overexpression of FKBP51 in idiopathic myelofibrosis regulates the growth factor independence of megakaryocyte progenitors. Blood. 2002, 100:2932-2940.
372.Iqbal, M.J. et al: Differentially abundant mRNAs in rat liver in response to diets containing soy protein isolate. Physiological Genomics. 2002, 11:219-226.
393.Valerius, M.T. et al: Hoxa 11 is upstream of integrin a8 expression in the developing kidney. Proc. Natl. Acad. Sci. USA. 2002, 99:8090-8095.
395.Lefebvre, B. et al: Chromosomal integration of retinoic acid response elements prevents cooperative transcriptional activation by retinoic acid receptor and retinoid x receptor. Mol. Cell. Biol. 2002, 22:1446-1459.
401.Matsuoka, T. et al: Members of the large maf transcription family regulate insulin gene transcription in islet § cells. Mol. Cell. Biol. 2003, 23:6049-6062.
402.Nguyen, M.M. et al: Requirement of PDZ-containing proteins for cell cycle regulation and differentiation in the mouse lens epithelium. Mol. Cell. Biol. 2003, 23:8970-8981.
407.Iida, H. et al: Complementary DNA cloning and characterization of rat spergen-2, a spermatogenic cell-specific gene 2 encoding a 56-kilodalton nuclear protein bearing ankyrin repeat motifs. Biol. Reproduction. 2003, 69:421-429.
408.Okulicz, W.C. and Ace, C.I.: Temporal regulation of gene expression during the expected window of receptivity in the rhesus monkey endometrium. Biol. Reproduction. 2003, 69:1593-1599.
409.Baran, N. et al: Decysin, a new member of the metalloproteinase family, is regulated by prolactin and dteroids during mouse pregnancy. Biol. Reproduction. 2003, 68:1787-1792.
424.Inagaki, T. et al: The retinoic acid-responsive proline-rich protein is identified in promyeloleukemic HL-60 cells. J. Biol. Chem. 2003, 278:51685-51692.
434.Chigira, S. et al: Increased expression of the huntingtin interacting protein-1 gene in cells from Hutchinson Gilford Syndrome (progeria) patients and aged donors. J. Gerontology Biol. Sci. Med. Sci. 2003, 58:B873-878.
438.Beyer, C. et al: Regulation of gene expression in the developing midbrain by estrogen: implication of classical and nonclassical steroid signaling. Ann. N.Y. Acad. Sci. 2003, 1007:17-28.
440.Scobey, M.J. et al: The Id2 transcriptional repressor is induced by follicle-stihormone and cAMP. J. Biol. Chem. 2004, 279:16064 - 16070.
460.Jaleel, M.A. et al: Stromal cell-derived factor-1 (SDF-1) signalling regulates human placental trophoblast cell survival. Molecular Human Reproduction. 2004, 10:901-909.
461.Iida, H. et al: Molecular cloning of rat Spergen-3, a spermatogenic cell-specific gene-3, encoding a novel 75-kDa protein bearing EF-hand motifs. J. Andrology. 2004, 25:885-892.
465.Shi, C. et al: Integrin engagement regulates monocyte differentiation through the forkhead transcription factor Foxp1. J. Clin. Invest. 2004, 114:408-418.
471.Thomas, E.K. et al: Endo180 binds to the c-terminal region of type I collagen. J. Biol. Chem., 2005, 280:22596-22605.
478.Lin, J.-C. and Tarn, W.-Y.: Exon selection in alpha-Tropomyosin mRNA is regulated by the antagonistic action of RBM4 and PTB. Mol. Cell. Biol., 2005, 25:10111-10121.
489.Paredes, A. et al: Loss of synaptonemal complex protein-1, a synaptonemal complex protein, contributes to the initiation of follicular assembly in the developing rat ovary. Endocrinology. 2005, 146:5267-5277.
502.Wang, S.-Z. et al: An oligodendrocyte-specific zinc-finger transcription regulator cooperates with Olig2 to promote oligodendrocyte differentiation. Development. 2006, 133:3389-3398.
504.Ishihata, A. and Katano, Y.: Investigation of differentially expressed genes in the ventricular myocardium of senescent rats. Ann. N.Y. Acad. Sci. 2006, 1067:142-151.

Signal Transduction and Growth Factor Actions

25.Sakuma et al: Radiation induction of the receptor tyrosine kinase gene ptk-3 in normal rat astrocytes. Radiation Research. 1995, 143:1-7.
27.Subramaniam, M. et al: Identification of a novel TGF-b-regulated gene encoding a putative zinc finger protein in human osteoblasts. Nucleic Acids Res. 1995, 23:4907-12.
30.Zhu, Y. et al: DUB-1, a deubiquitinating enzyme with growth suppressing activity. Proc. Natl. Acad. Sci. USA. 1996, 93:3275-79.
44.Wang, X. et al: Interferon-inducible protein-10 involves vascular smooth muscle cell migration, proliferation, and inflammatory response. J. Biol. Chem. 1996, 271:24286-24293.
46.Taylor, G.A. et al: Identification of a novel GTPase, the inducibly expressed GTPase, that accumulates in response to interferon [gamma]. J. Biol. Chem. 1996, 271:20399-20405.
59.Robinson, L. et al: ETS target genes: Identification of Egr1 as a target by RNA differential display and whole genome PCR techniques. Proc. Natl. Acad. Sci. USA. 1997, 94:7170-7175.
61.Pendurthi, U.R. et al: Binding of factor VIIa to tissue factor induces alterations in gene expression in human fibroblast cells: up-regulation of poly(A) polymerase. Proc. Natl. Acad. Sci. USA. 1997, 94:12598-12603.
63.Bartl, S. et al.: Identification of mouse histone deacetylase 1 as a growth factor-inducible gene. Mol. Cell. Biol. 1997, 17:5033-43.
78.Kothapalli, R. et al: Detection of ebaf, a novel human gene of the transforming growth factor b superfamily: Association of gene expression with endometrial bleeding. J. Clin. Invest. 1997, 99:2342-2350.
91.Padanilam, B.J. and Hammerman, M.R.: Ischemia-induced receptor for activated C kinase (RACK1) expression in rat kidneys. Am. J. Physiol: Renal Physiology. 1997, 272:F160-166.
106.Chacko, G. et al: Induction of acute translational response genes by homocysteine: Elongation factors-1-µ, -b, -d. J. Biol. Chem. 1998, 273:19840-19846.
108.Du, M. et al: Cloning and expression analysis of a novel salicylate suppressible gene, Hs-CUL-3, a member of cullin/Cdc53 family. J. Biol. Chem. 1998, 273:24289-24292.
110.Zentner, M.D. et al: The amiloride-sensitive epithelial sodium channel a-subunit is transcriptionally down-regulated in rat parotid cells by the extracellular signal-regulated protein kinase pathway. J. Biol. Chem. 1998, 273:30770-30776.
111.Austin, R.C. et al: Homocysteine-dependent alterations in mitochondrial gene expression, function and structure: Homocysteine and H2O2 act synergistically to enhance mitochondrial damage. J. Biol. Chem. 1998, 273:30808-30817.
115.Chung, K.-C. et al: Raf and fibroblast growth factor phosphorylate Elk1 and activate the serum response element of the immediate early gene pip92 by mitogen-activated protein kinase-independent as well as -dependent signaling pathways. Mol. Cell. Biol. 1998, 18:2272-2281.
242.Taylor, G.A. et al: Regulation of P311 expression by Met-hepatocyte growth factor/scatter factor and the ubiquitin/proteasome system. J. Biol. Chem. 2000, 275:4215-4219.
244.Hu, Q. and Maity, S.N.: Stable expression of a dominant negative mutant of CCAAT binding factor/NF-Y in mouse fibroblast cells resulting in retardation of cell growth and inhibition of transcription of various cellular genes. J. Biol. Chem. 2000, 275:4435-4444.
250.Zhang, R. et al: Identification of a novel ligand-receptor pair constitutively activated by Ras oncogenes. J. Biol. Chem. 2000, 275:24436-24443.
278.Moriwaki, Y. et al: Mycobacterium bovis Bacillus calmette-guerin and its cell wall complex induce a novel lysosomal membrane protein, SIMPLE, that bridges the missing link between lipopolysaccharide and p53-inducible Gene, LITAF(PIG7), and estrogen-inducible gene, EET-1. J. Biol. Chem. 2001, 276:23065-23076.
283.Poligone, B. and Baldwin, A.S.: Positive and negative regulation of NF-kB by COX-2. Roles of different prostaglandins. J. Biol. Chem. 2001, 276:38658-38664.
290.Jhaveri, M.S. et al: Impact of extracellular folate levels on global gene expression. Mol. Pharmacology. 2001, 60:1288-1295.
313.Yamada, T. et al: Lineage switch induced by overexpression of Ets family transcription factor PU.1 in murine erythroleukemia cells. Blood. 2001, 97:2300-2307.
315.Thai, S. et al: Detection of early gene expression changes by differential display in the livers of mice exposed to dichloroacetic acid. Carcinogenesis. 2001, 22:1317-1322.
318.Doi, M. et al: Light-induced phase-delay of the chicken pineal circadian clock is associated with the induction of cE4bp4, a potential transcriptional repressor of cPer2 gene. Proc. Natl. Acad. Sci. USA. 2001, 98:8089-8094.
324.Kretzler, M. et al: Integrin linked kinase as a candidate downstream effector in proteinuria. FASEB J. 2001, 10.1096/fj.00-0832fje.
342.Rousseau, S. et al: Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAs. EMBO J. 2002, 21:6505-6514.
343.Jiao, X. et al: Identification of target messenger RNA substrates for the murine deleted in azoospermia-like RNA-binding protein. Biol. Reproduction. 2002, 66:475-485.
348.Wolf, G. et al: Angiotensin IIŐs antiproliferative effects mediated through AT2-receptors depend on down-regulation of SM-20. Laboratory Investigation. 2002, 82:1305-1317.
350.Wang, M. et al: Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2. J. Biol. Chem. 2002, 277:7341-7347.
352.Christian, M. et al: Cyclic AMP-induced forkhead transcription factor, FKHR, cooperates with CCAAT/enhancer-binding protein b in differentiating human endometrial stromal cells. J. Biol. Chem. 2002, 277:20825-20832.
354.Cunningham, S.A. et al: JAM2 interacts with a4b1, facilitation by JAM3. J. Biol. Chem. 2002, 277:27589-27592.
356.McCudden, C.R. et al: Characterization of mammalian stanniocalcin receptors. Mitochondrial targeting of ligand and receptor for regulation of cellular metabolism. J. Biol. Chem. 2002, 277:45249-45258.
368.Giraudier, S. et al: Overexpression of FKBP51 in idiopathic myelofibrosis regulates the growth factor independence of megakaryocyte progenitors. Blood. 2002, 100:2932-2940.
395.Lefebvre, B. et al: Chromosomal integration of retinoic acid response elements prevents cooperative transcriptional activation by retinoic acid receptor and retinoid x receptor. Mol. Cell. Biol. 2002, 22:1446-1459.
401.Matsuoka, T. et al: Members of the large maf transcription family regulate insulin gene transcription in islet § cells. Mol. Cell. Biol. 2003, 23:6049-6062.
423.Satake, H. et al: Genes modulated by expression of GD3 synthase in Chinese hamster ovary cells, evidence that the Tis21 gene is now involved in the induction of GD3 9-0-acetylation. J. Biol. Chem. 2003, 278:7942-7948.
428.P‡ez-Pereda, M. et al: Involvement of bone morphogenetic protein 4 (BMP-4) in pituitary prolactinoma pathogenesis through a Smad/estrogen receptor crosstalk. Proc. Natl. Acad. Sci. USA. 2003, 100:1034-1039.
437.Luo, Y. et al: Development of Nurr1 stable cell lines for the identification of downstream targets. Ann. N.Y. Acad. Sci. 2003, 991:354-358.
444.Dong, G. et al: Metastatic squamous cell carcinoma cells that overexpress c-Met exhibit enhanced angiogenesis factor expression, scattering and metastasis in response to hepatocyte growth factor. Oncogene. 2004, 23:6199-6208.
462.Coupel, S. et al: RhoA activation mediates phosphatidylinositol 3-kinaseĐdependent proliferation of human vascular endothelial cells: An alloimmune mechanism of chronic allograft nephropathy. J. Am. Soc. Nephrology. 2004, 15:2429-2439.
475.Bardeesy, N. et al: Role of epidermal growth factor receptor signaling in RAS-driven melanoma. Mol. Cell. Biol. 2005, 25:4176-4188.
488.Trevaskis, J. et al: Src Homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1, a novel neuronal protein that regulates energy balance. Endocrinology. 2005, 146:3757-3764.
492.Tang, D.C. et al: The hydroxyurea-induced small GTP-binding protein SAR modulates gamma-globin gene expression in human erythroid cells. Blood. 2005, 106:3256-3263.

Immunology and Cytokine Actions

51.Sheikh-Hamad, D. et al: CD9 antigen mRNA is induced by hypertonicity in two renal epithelial cell lines. Am. J. Physiol: Cell Physiology. 1996, 270:C253-258.
52.Jin, F. et al: Secretory leukocyte protease inhibitor: a macrophage product induced by and antagonistic to bacterial lipopolysaccharide. Cell. 1997, 88:417-26.
64.Kuno, K. et al: Molecular cloning of a gene encoding a new type of metalloproteinase-disintegrin family protein with thrombospondin motifs as an inflammation associated gene. J. Biol. Chem. 1997, 272:556-562.
67.Dong, L. et al: Down-regulation of major histocompatibility complex Q1b gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin. J. Biol. Chem. 1997, 272:29614-29619.
76.Yamada, E. et al: Differential display analysis of murine collagen-induced arthritis: cloning of the cDNA-encoding murine ATPase inhibitor. Immunology. 1997, 92:571-576.
79.Li. Y. and Youssoufian, H.: MxA overexpression reveals a com-mon genetic link in four Fanconi anemia complementation groups. J. Clin. Invest. 1997, 100:2873-2880.
102.Dandoy-Dron, F. et al: Gene expression in Scrapie. Cloning of a new Scrapie-responsive gene and the identification of increased levels of seven other mRNA transcripts. J. Biol. Chem. 1998, 273:7691-7697.
109.Badea, T.C. et al: Molecular cloning and characterization of RGC-32, a novel gene induced by complement activation in oligodendrocytes. J. Biol. Chem. 1998, 273:26977-26981.
127.Sun, H.B. et al: MRG1, the product of a melanocyte-specific gene related gene, is a cytokine-inducible transcription factor with transformation activity. Proc. Natl. Acad. Sci. USA. 1998, 95:13555-13560.
133.Morikawa, Y. et al: Induction of synaptosomal-associated protein-23 kD (SNAP-23) by various cytokines. Blood. 1998, 92:129-135.
134.Xu, D. et al: Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cells. J. Experimental Medicine. 1998, 187:787-794.
138.Chen, J. et al: Eotaxin and capping protein in experimental vasculopathy. American Journal of Pathology. 1998, 153:81-90.
141.Li, X.-L. et al: RNase L mediates the antiviral effect of interferon through a selective reduction in viral RNA during Encephalomyocarditis virus infection. J. Virology. 1998, 72:2752-2759.
189.Ahlers, C. et al: Cyclosporin A inhibits Ca2+-mediated upregulation of the DNA repair enzyme DNA polymerase b in human peripheral blood mononuclear cells. European J. Biochem. 1999, 264:952-959.
205.Qiu F.-H. et al: IMP and AMP deaminase in reperfusion injury down-regulates neutrophil recruitment. Proc. Natl. Acad. Sci. USA. 2000, 97:4267-4272.
225.Tang, X. et al: Down-regulation of GATA-2 transcription during Pneumocystis carinii infection. Infection and Immunity. 2000, 68:4720-4724.
245.Li, X.-L. et al: RNase-L-dependent destabilization of interferon-induced mRNAs - A role for the 2-5A system in attenuation of the interferon response. J. Biol. Chem. 2000, 275:8880-8888.
262.Attur, M.G. et al: Functional genomic analysis in arthritis-affected cartilage: yin-yang regulation of inflammatory mediators by a5§1 and aV§3 integrins. J. Immunolgy. 2000, 164:2684-2691.
279.Huang, W. et al: The nucleolar phosphoprotein B23 interacts with hepatitis delta antigens and modulates the hepatitis delta virus RNA replication. J. Biol. Chem. 2001, 276:25166-25175.
283.Poligone, B. and Baldwin, A.S.: Positive and negative regulation of NF-kB by COX-2. Roles of different prostaglandins. J. Biol. Chem. 2001, 276:38658-38664.
310.Guenzi, E. et al: The helical domain of GBP-1 mediates the inhibition of endothelial cell proliferation by inflammatory cytokines. EMBO J. 2001, 20:5568-5577.
311.Lacy, H.M. and Sanderson, R.D.: Sperm protein 17 is expressed on normal and malignant lymphocytes and promotes heparan sulfate-mediated cell-cell adhesion. Blood. 2001, 98:2160-2165.
312.Gregorio-King, C.C. et al: ORP-3, a human oxysterol-binding protein gene differentially expressed in hematopoietic cells. Blood. 2001, 98:2279-2281.
330.Boulday, G. et al: Antigraft antibody-mediated expression of metalloproteinases on endothelial cells : differential expression of TIMP-1 and ADAM-10 depends on antibody specificity and isotype. Circulation Research. 2001, 88:430-437.
342.Rousseau, S. et al: Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAs. EMBO J. 2002, 21:6505-6514.
350.Wang, M. et al: Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2. J. Biol. Chem. 2002, 277:7341-7347.
363.GutiŽrrez-Pabello, J.A. et al: Upregulation of Thymosin §-10 by Mycobacterium bovis infection of bovine macrophages is associated with apoptosis. Infection and Immunity. 2002, 70:2121-2127.
364.Sebert, M.E. et al: Microarray-based identification of htrA, a Streptococcus pneumoniae gene that is regulated by the CiaRH two-component system and contributes to nasopharyngeal colonization. Infection and Immunity. 2002, 70:4059-4067.
365.Swords, W.E. et al: Acylation of the lipooligosaccharide of haemophilus influenzae and colonization: an htrB mutation diminishes the colonization of human airway epithelial cells. Infection and Immunity. 2002, 70:4661-4668.
366.Rude, T.H. et al: Relationship of the glyoxylate pathway to the pathogenesis of Cryptococcus neoformans. Infection and Immunity. 2002; 70:5684-5694.
381.Walder, K. et al: Tanis: a link between type 2 diabetes and inflammation? Diabetes. 2002, 51:1859-1866.
388.Richard, M. et al: The expression pattern of the ITIM-bearing lectin CLECSF6 in neutrophils suggests a key role in the control of inflammation. J. Leukoc. Biol. 2002, 71:871-880.
405.Warke, R.V. et al: Dengue virus induces novel changes in gene expression of human umbilical vein endothelial cells. J. Virology. 2003, 77:11822-11832.
411.Luberto, C. et al: Identification of App1 as a regulator of phagocytosis and virulence of Cryptococcus neoformans. J. Clin. Invest. 2003, 112:1080-1094.
435.El-Gedaily, A. et al: Constitutive and regulated expression of platelet basic protein in human monocytes. J. Leukoc. Biol. 2003, 10.1189-jlb.0603288.
436.Tran, H. et al: Modulation of the LDL receptor and LRP levels by HIV protease inhibitors. J. Lipid Research. 2003, 44:1859-1869.
442.Tam, S.-Y. et al: RabGEF1 is a negative regulator of mast cell activation and skin inflammation. Nature Immunology. 2004, 5:844-852.
454.Begum, N.A. et al: Mycobacterium bovis BCG cell wall-specific differentially expressed genes identified by differential display and cDNA subtraction in human macrophages. Infection and Immunity. 2004, 72:937-948.
463.Reiser, J. et al: Induction of B7-1 in podocytes is associated with nephrotic syndrome. J. Clin. Invest. 2004, 113:1390-1397.
464.Carlson, K.A. et al: Molecular characterization of a putative antiretroviral transcriptional factor, OTK18. J. Immunology. 2004, 172:381-391.
490.Lamerant, N. and Kieda, C.: Adhesion properties of adhesion-regulating molecule 1 protein on endothelial cells. FEBS J. 2005, 272:1833-1844.
503.Schnell, S. et al: Gimap4 accelerates T-cell death. Blood. 2006, 108:591-599.

Endocrine Biology and Hormone Actions

40.Averboukh, L. et al: Regulation of S100P expression by androgen. The Prostate. 1996, 29:350-55.
56.Montano, M.M. and Katzenellenbogen, B.S.: The quinone reductase gene: a unique estrogen receptor-regulated gene that is activated by antiestrogens. Proc. Natl. Acad. Sci. USA. 1997, 94:2581-2586.
57.Lin, T.-M. and Chang, C.: Cloning and characterization of TDD5, an androgen target gene that is differentially repressed by testosterone and dihydrotestosterone. Proc. Natl. Acad. Sci. USA. 1997, 94:4988-4993.
71.Everett L.M. et al: A novel estrogen-enhanced transcript identified in the rat uterus by differential display. Endocrinology. 1997, 138:3836-3841.
95.Garnier, M. et al: Identification of estrogen-responsive genes in neuroblastoma SK-ER3 cells. Journal of Neuroscience. 1997, 17:4591-4599.
100.Kemppainen, R.J. and Behrend, E.N.: Dexamethasone rapidly induces a novel Ras superfamily member-related gene in AtT-20 cells. J. Biol. Chem. 1998, 273:3129-3131.
107.Tabor, D.E. et al: Transcriptional activation of the Stearoyl-CoA desaturase 2 gene by sterol regulatory element-binding protein/adipocyte determination and differentiation Factor 1. J. Biol. Chem. 1998, 273:22052-22058.
120.Fang, Z. et al: Identification of novel factors that regulate GnRH gene expression and neuronal migration. Endocrinology. 1998, 39:3654-3657.
143.Matsuba, T. et al: Identification of glucocorticoid- and adenovirus E1A-regulated genes in lung epithelial cells by differential display. American J. Respiratory Cell & Mol. Biol. 1998, 18:243-254.
144.Chen, J. et al: Enhanced levels of several mitochondrial mRNA transcripts and mitochondrial superoxide production during ethinyl estradiol-induced hepatocarcinogenesis and after estrogen treatment of HepG2 cells. Carcinogenesis. 1998, 19:2187-2193.
157.Chen, D. et al: Cloning and uterus/oviduct-specific expression of a novel estrogen-regulated gene (ERG1). J. Biol. Chem. 1999, 274:32215-32224.
159.Dieudonne, S.C. et al: Differential display of human marrow stromal cells reveals unique mRNA expression patterns in response to dexamethasone. J. Cellular Biochemistry. 1999, 76:231-243.
177.Krebs, C.J. et al: The 70-kDa heat shock cognate protein (Hsc73) gene is enhanced by ovarian hormones in the ventromedial hypothalamus. Proc. Natl. Acad. Sci. USA. 1999, 96:1686-1691.
195.Chen, D. et al: Potential regulation of membrane trafficking by estrogen receptor via induction of Rab11 in uterine glands during implantation. Mol. Endocrinology. 1999, 13:993-1004.
206.Krebs, C.J. et al: A membrane-associated progesterone-binding protein, 25-Dx, is regulated by progesterone in brain regions involved in female reproductive behaviors. Proc. Natl. Acad. Sci. USA. 2000, 97:12816-12821.
214.Espey, L.L. et al: Induction of early growth response protein-1 gene expression in the rat ovary in response to an ovulatory dose of human chorionic gonadotropin. Endocrinology. 2000, 141:2385-2391.
215.Yoshioka, S. et al: Expression of tumor necrosis factor-stimulated gene-6 in the rat ovary in response to an ovulatory dose of gonadotropin. Endocrinology. 2000, 41:4114-4119.
216.Espey, L.L. et al: Characterization of ovarian carbonyl reductase gene expression during ovulation in the gonadotropin-primed immature rat. Biol. Reproduction. 2000, 62:390-397.
218.Espey, L.L. et al: Ovarian expression of a disintegrin and metalloproteinase with thrombospondin motifs during ovulation in the gonadotropin-primed immature rat. Biol. Reproduction. 2000, 62:1090-1095.
219.Ujioka, T. et al: Expression of regulator of G-protein signaling protein-2 in the rat ovary at the time of ovulation. Biol. Reproduction. 2000, 63:1513-1517.
224.Chinoy, M.R. et al: Dexamethasone enhances ras-recision gene expression in cultured murine fetal lungs: role in development. Am. J. Physiol: Lung Cell. & Molec. Physiol. 2000, 279:312L-318L.
232.Dowling, A.L.S. et al: Acute changes in maternal thyroid hormone induce rapid and transient changes in gene expression in fetal rat brain. Journal of Neuroscience. 2000, 20:2255-2265
273.Eisenhofer, G. et al: Pheochromocytomas in von Hippel-Lindau Syndrome and multiple endocrine neoplasia type 2 display distinct biochemical and clinical phenotypes. J. Clin. Endocrinology & Metabolism. 2001, 86:1999-2008.
274.Kumar, S. et al: Messenger ribonucleic acid encoding interferon-inducible guanylate binding protein 1 is induced in human endometrium within the putative window of implantation. J. Clin. Endocrinology & Metabolism. 2001, 86:2420-2427
319.Harris, H.A. et al: Regulation of metallothionein II messenger ribonucleic acid measures exogenous estrogen receptor-§ activity in SAOS-2 and LNCaPLN3 cells. Endocrinology. 2001, 142:645-652.
320.Huynh, H. et al: Induction of UO-44 gene expression by tamoxifen in the rat uterus and ovary. Endocrinology. 2001, 142:2985-2995.
321.Huynh, H. et al: Cloning and characterization of a novel pregnancy-induced growth inhibitor in mammary gland. Endocrinology. 2001, 142:3607-3615
322.Espey, L.L. et al: 3-Hydroxysteroid dehydrogenase messenger RNA transcription in the immature rat ovary in response to an ovulatory dose of gonadotropin. Biol. Reproduction. 2001;65:72-78.
323.Edgar, A.J. et al: Cloning of dexamethasone-induced transcript : a novel glucocorticoid-induced gene that is upregulated in emphysema. Am. J. Respiratory Cell Molecular Biology. 2001, 25:119-124.
326.Bobe, J. and Goetz, F.W.: An ovarian progastricsin is present in the trout coelomic fluid after ovulation. Biol. Reproduction. 2001, 64:1048-1055.
345.Baran, N. et al: Characterization of a prolactin-regulated gene in reproductive tissues using the prolactin receptor knockout mouse model. Biol. Reproduction. 2002, 66:1210-1218.
347.Espey, L.L. and Richards, J.S.: Temporal and spatial patterns of ovarian gene transcription following an ovulatory dose of gonadotropin in the rat. Biol. Reproduction. 2002, 67:1662-1670.
357.Mong, J.A. et al: Perspective: micoarrays and differential display PCRŃtools for studying transcript levels of genes in neuroendocrine systems. Endocrinology. 2002, 143:2002-2006.
386.Ahola, T.M. et al: Progestin upregulates G-protein-coupled receptor 30 in breast cancer cells. European J. Biochem. 2002, 269:2485-2490.
401.Matsuoka, T. et al: Members of the large maf transcription family regulate insulin gene transcription in islet § cells. Mol. Cell. Biol. 2003, 23:6049-6062.
404.Bogatcheva, N.V. et al: GREAT/LGR8 is the only receptor for insulin-like 3 peptide. Mol. Endocrinology. 2003, 17:2639-2646.
408.Okulicz, W.C. and Ace, C.I.: Temporal regulation of gene expression during the expected window of receptivity in the rhesus monkey endometrium. Biol. Reproduction. 2003, 69:1593-1599.
409.Baran, N. et al: Decysin, a new member of the metalloproteinase family, is regulated by prolactin and dteroids during mouse pregnancy. Biol. Reproduction. 2003, 68:1787-1792.
410.Espey, L.L. et al: Cells of the rat ovary during the periovulatory period. Biol. Reproduction. 2003, 68:1895-1902.
428.P‡ez-Pereda, M. et al: Involvement of bone morphogenetic protein 4 (BMP-4) in pituitary prolactinoma pathogenesis through a Smad/estrogen receptor crosstalk. Proc. Natl. Acad. Sci. USA. 2003, 100:1034-1039.
440.Scobey, M.J. et al: The Id2 transcriptional repressor is induced by follicle-stihormone and cAMP. J. Biol. Chem. 2004, 279:16064 - 16070.
474.Jacques, C. et al: Two-step differential expression analysis reveals a new set of genes involved in thyroid oncocytic tumors. J. Clin. Endocrinology & Metabolism. 2005, 90:2314-2320.
486.Mutsuga, N. et al: Regulation of gene expression in magnocellular neurons in rat supraoptic nucleus during sustained hypoosmolality. Endocrinology. 2005, 146:1254-1267.
487.Hung, H.: Suppression of ps20 expression in the rat uterus by tamoxifen and estrogens. Endocrinology. 2005, 146:2388-2396.
488.Trevaskis, J. et al: Src Homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1, a novel neuronal protein that regulates energy balance. Endocrinology. 2005, 146:3757-3764.
489.Paredes, A. et al: Loss of synaptonemal complex protein-1, a synaptonemal complex protein, contributes to the initiation of follicular assembly in the developing rat ovary. Endocrinology. 2005, 146:5267-5277.

Neuroscience

19.Douglass et al: PCR differential display identifies a rat brain mRNA that is transcriptionally regulated by cocaine and amphetamine. J. Neurosciences. 1995, 15:2471-81.
42.Green, C.B. et al: Use of a high stringency differential display screen for identification of retinal mRNAs that are regulated by a circadian clock. Molecular Brain Research. 1996, 37:157-65.
43.Green, C.B. et al: Identification of a novel vertebrate circadian clock-regulated gene encoding the protein nocturnin. Proc. Natl. Acad. Sci. USA. 1996, 93:14884-88.
49.Crino, P.B. and Eberwine, J.: Molecular characterization of the dendritic growth cone: regulated mRNA transport and local protein synthesis. Neuron. 1996, 17:1173-1187.
65.Conti, B. et al: Induction of interferon-[gamma] inducing factor in the adrenal cortex. J. Biol. Chem. 1997, 272:2035-2037.
70.Flanigan, T.P. and Leslie R.A.: Changes in brain gene expression in psychiatric illnessŃmRNA differential display provides some clues. Molecular Psychiatry. 1997, 2:451-456.
73.Livesey, F.J. et al: A Schwann cell mitogene accompanying regeneration of motor neurons. Nature. 1997, 390:614-618.
80.Tohda, C. et al: Increased expression of mRNA for myocyte-specific enhancer binding factor (MEF) 2C in the cerebral cortex of the itching mouse. Neuroscience Research. 1997, 29:209-215.
89.Liu, Q.-R. et al: A developmental gene (Tolloid/BMP-1) is regulated in Aplysia neurons by treatments that induce long-term sensitization. Journal of Neuroscience. 1997, 17:755-764.
95.Garnier, M. et al: Identification of estrogen-responsive genes in neuroblastoma SK-ER3 cells. Journal of Neuroscience. 1997, 17:4591-4599.
98.Lawlor, E.R. et al: The Ewing tumor family of peripheral primitive neuroectodermal tumors expresses human gastrin-releasing peptide. Cancer Research. 1998, 58:2469-2476.
102.Dandoy-Dron, F. et al: Gene expression in Scrapie. Cloning of a new Scrapie-responsive gene and the identification of increased levels of seven other mRNA transcripts. J. Biol. Chem. 1998, 273:7691-7697.
109.Badea, T.C. et al: Molecular cloning and characterization of RGC-32, a novel gene induced by complement activation in oligodendrocytes. J. Biol. Chem. 1998, 273:26977-26981.
118.Nagano, T. et al: Differentially expressed olfactomedin-related glycoproteins (pancortins) in the brain. Molecular Brain Research. 1998, 53:13-23.
119.Wang, X.B. and Uhl, G.R.: Subtracted differential display - genes with amphetamine-altered expression patterns include calcineurin. Molecular Brain Research. 1998, 53:344-347.
120.Fang, Z. et al: Identification of novel factors that regulate GnRH gene expression and neuronal migration. Endocrinology. 1998, 39:3654-3657.
147.Krushel, L.A. et al: NF-KB activity is induced by neural cell adhesion molecule binding to neurons and astrocytes. J. Biol. Chem. 1999, 274:2432-2439.
158.Akiyama, H. et al: Molecular cloning and biological activity of a novel Ha-Ras suppressor gene predominantly expressed in skeletal muscle, heart, brain, and bone marrow by differential display using clonal mouse EC cells, ATDC5. J. Biol. Chem. 1999, 274:32192-32197.
172.OŐHara, B.F. et al: Gene expression in the brain across the hibernation cycle. Journal of Neuroscience. 1999, 19:3781-3790.
173.Gomi, H. et al: Learning induces a CDC2-related protein kinase, KKIAMRE. Journal of Neuroscience. 1999, 19:9530-9537.
182.Wang, J.-F. et al: Differential display PCR reveals novel targets for the mood-stabilizing drug valproate including the molecular chaperone GRP78. Mol. Pharmacology. 1999, 55:521-527.
191.Liu, H. et al: Isolation of 10 differentially expressed cDNAs in differentiated Neuro2a cells induced through controlled expression of the GD3 synthase gene. J. Neurochemistry. 1999, 72:1781-1790.
192.Gomes, I. et al: A proline- and glutamine-rich protein promotes apoptosis in neuronal cells. J. Neurochemistry. 1999, 73:612-622.
196.Chen, G. et al: The mood-stabilizing agents lithium and valproate robustlIncrease the levels of the neuroprotective protein bcl-2 in the CNS. J. Neurochemistry. 1999, 72:879-882.
206.Krebs, C.J. et al: A membrane-associated progesterone-binding protein, 25-Dx, is regulated by progesterone in brain regions involved in female reproductive behaviors. Proc. Natl. Acad. Sci. USA. 2000, 97:12816-12821.
209.Chan, J.R. et al: Progesterone synthesized by Schwann cells during myelin formation regulates neuronal gene expression. Mol. Biol. of the Cell. 2000, 11:2283-2295.
230.Fujii, S. et al: Differential expression of neuroendocrine-specific protein in form-deprived chick eyes. Invest. Ophthalmology & Vis. Sci. 2000, 41:1533-1541.
231.Feldkaemper, M.P. et al: Changes in retinal and choroidal gene expression during development of refractive errors in chicks. Invest. Ophthalmology & Vis. Sci. 2000, 41:1623-1628.
232.Dowling, A.L.S. et al: Acute changes in maternal thyroid hormone induce rapid and transient changes in gene expression in fetal rat brain. Journal of Neuroscience. 2000, 20:2255-2265
238.Denisenko-Nehrbass, N.I. et al: Site-specific retinoic acid production in the brain of adult songbirds. Neuron. 2000, 27:359-370.
242.Taylor, G.A. et al: Regulation of P311 expression by Met-hepatocyte growth factor/scatter factor and the ubiquitin/proteasome system. J. Biol. Chem. 2000, 275:4215-4219.
275.DeGregorio-Rocasolano, N. et al: Overexpression of neuronal pentraxin 1 is involved in neuronal death evoked by low K+ in cerebellar granule cells. J. Biol. Chem. 2001, 276:796-803.
291.Sahir, N. et al: Caffeine-induced telencephalic vesicle evagination in early post-implantation mouse embryos involves cAMP-dependent protein kinase (PKA) inhibition. Cerebral Cortex. 2001, 11:343-349.
301.Thakker-Varia, S. et al: Rab3A is required for brain-derived neurotrophic factor-induced synaptic plasticity: transcriptional analysis at the population and single-cell levels. J. Neurosciences. 2001, 21:6782-6790.
318.Doi, M. et al: Light-induced phase-delay of the chicken pineal circadian clock is associated with the induction of cE4bp4, a potential transcriptional repressor of cPer2 gene. Proc. Natl. Acad. Sci. USA. 2001, 98:8089-8094.
331.Watakabe, A. et al: Growth/differentiation factor 7 is preferentially expressed in the primary motor area of the monkey neocortex. J. Neurochemistry. 2001, 76:1455-1464.
332.Sumi, S. et al: Isolation and characterization of the genes up-regulated in isolated neurons by aged garlic extract (AGE). J. Nutrition. 2001, 131:1096S-1099.
357.Mong, J.A. et al: Perspective: micoarrays and differential display PCRŃtools for studying transcript levels of genes in neuroendocrine systems. Endocrinology. 2002, 143:2002-2006.
362.Yang, C.B. et al: Identification of Munc13-3 as a candidate gene for critical-period neuroplasticity in visual cortex. J. Neurosciences. 2002, 22:8614-8618.
371.Yoshida-Hiroi, M. et al: Chromaffin cell function and structure is impaired in corticotropin-releasing hormone receptor type 1-null mice. Molecular Psychiatry. 2002, 7:967-974.
380.Hong, J. et al: Characterization of a cysteine proteinase inhibitor induced during neuronal cell differentiation. J. Neurochem. 2002, 81:922-934.
392.Tsai, K.J. et al: sgk, a primary glucocorticoid-induced gene, facilitates memory consolidation of spatial learning in rats. Proc. Natl. Acad. Sci. USA. 2002, 99:3990-3995.
430.Kajimoto, Y. et al: Synapse-associated protein 90/postsynaptic density-95-associated protein (SAPAP) is expressed differentially in phencyclidine-treated rats and is increased in the nucleus accumbens of patients with schizophrenia. Neuropsychopharmacology. 2003, 28:1831-1839.
438.Beyer, C. et al: Regulation of gene expression in the developing midbrain by estrogen: implication of classical and nonclassical steroid signaling. Ann. N.Y. Acad. Sci. 2003, 1007:17-28.
449.Mori, M. et al: Expression of apoptosis inhibitor protein Mcl1 linked to neuroprotection in CNS neurons. Cell Death and Differentiation. 2004, 11:1223-1233.
453.Shelton, R.C. et al: Differential expression of Pentraxin 3 in fibroblasts from patients with major depression. Neuropsychopharmacology. 2004, 29:126-132.
455.Brinks, H. et al: The repulsive guidance molecule RGMa is involved in the formation of afferent connections in the dentate gyrus. Journal of Neuroscience. 2004, 24:3862-3869.
456.Sokolowski, B.H.A. et al: Identification and localization of an arachidonic acid-sensitive potassium channel in the cochlea. Journal of Neuroscience. 2004, 24:6265-6276.
457.de Yebra L. et al: Reduced KIAA0471 mRNA expression in Alzheimer's patients: a new candidate gene product linked to the disease? Hum. Mol. Genet. 2004, 13:2607-2612.
458.Huang, H. et al: Downregulation of ATP synthase subunit-6, cytochrome c oxidase-III, and NADH dehydrogenase-3 by bright cyclic light in the rat retina. Invest. Ophthalmology & Vis. Sci. 2004, 45:2489-2496.
481.Komatsu, Y. et al: Retinol-binding protein gene is highly expressed in higher-order association areas of the primate neocortex. Cerebral Cortex. 2005, 15:96-108.
482.Panepinto, J. et al: The DEAD-box RNA helicase Vad1 regulates multiple virulence-associated genes in Cryptococcus neoformans. J. Clin. Invest. 2005, 115:632-641.
486.Mutsuga, N. et al: Regulation of gene expression in magnocellular neurons in rat supraoptic nucleus during sustained hypoosmolality. Endocrinology. 2005, 146:1254-1267.
488.Trevaskis, J. et al: Src Homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1, a novel neuronal protein that regulates energy balance. Endocrinology. 2005, 146:3757-3764.
502.Wang, S.-Z. et al: An oligodendrocyte-specific zinc-finger transcription regulator cooperates with Olig2 to